3-Isomangostin - CAS 19275-46-8

3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well.

MTH1, DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

19221

0.999

C24H26O6

410.46

COc1c(O)cc2oc3cc4OC(C)(C)CCc4c(O)c3c(=O)c2c1CC=C(C)C

-20°C

Ice Packs

Natural Product