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Molfinity

3-MATIDA - CAS 518357-51-2

3-MATIDA - CAS 518357-51-2

SKU:MF-0015727-01

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  • Bioactivity

    3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a) . Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM) . 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.

  • Target

    NMDAR, Others, GluR

  • Related Pathways

    Neuroscience, Others

  • CAS Number

    518304

  • Purity

    0.9996

  • Molecular Formula

    C8H9NO4S

  • Molecular Weight

    215.23

  • SMILES

    C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound