Molfinity
3-O-methyl Estradiol - CAS 1035-77-4
3-O-methyl Estradiol - CAS 1035-77-4
SKU:MF-0057652-01
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Product Details
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Bioactivity
3-O-methyl Estradiol is a synthetic estrogen known for its ability to interfere with microtubule networks in V79 Chinese hamster cells, with an EC50 value of 9 μM. At a concentration of 20 μM, it inhibits the proliferation of these cells by 92%. Additionally, when male rats on a high-cholesterol diet are administered 3-O-methyl Estradiol (25 mg in a 0.2 ml solution, p.o.), it results in decreased serum cholesterol levels and increases body weight loss, suggesting feminizing effects. It has also been utilized as a standard for quantifying 17β-estradiol in hen urine.
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Target
Others
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Related Pathways
Others
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CAS Number
954
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Molecular Formula
C19H26O2
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Molecular Weight
286.41
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SMILES
C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound