3-Oxo-5β-cholanoic acid - CAS 1553-56-6

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) is a bile acid metabolite that inhibits TH17 cell differentiation by directly binding to the transcription factor RORγt with a Kd of 1.13 μM.

ROR

Metabolism

1491

0.9986

C24H38O3

374.56

C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

-20°C

Ice Packs

Natural Product