3-sucCA - CAS 94159-47-4

3-SucCA (3-Succinylated cholic acid), a bile acid derived from microbial sources, primarily functions as a lumen-restricted metabolite. It plays a crucial role in mitigating the progression of MAFL-MASH in mouse models by altering the gut microbiota composition, notably by enhancing the proliferation of Akkermansia muciniphila. Notably, lower levels of 3-sucCA have been observed in patients with biopsy-proven MAFLD.

Others, Endogenous Metabolite, Antibacterial

Others, Metabolism, Microbiology/Virology

94159-47-4

C28H44O8

508.64

O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](OC(CCC(O)=O)=O)CC4)[H])[H])[H])[H]

-20°C

Ice Packs

Small Compound