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Molfinity
3A-MPLA - CAS 1699735-80-2
3A-MPLA - CAS 1699735-80-2
SKU:MF-0057826-01
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Product Details
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Bioactivity
Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4) . It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL) -1β, however not as efficient as lipopolysaccharide (LPS) . MPLA improves immune response during bacterial sepsis infection.
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Target
Others, TLR
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
1699653
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Molecular Formula
C54H106N3O17P
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Molecular Weight
1100.42
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SMILES
[NH4+].CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](CO)O[C@H]1OC[C@H]1O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](O)[C@@H]1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound