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Molfinity

3PO - CAS 18550-98-6

3PO - CAS 18550-98-6

MF-0018206-01

$48.87 USD
$48.87 USD
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Product Details

  • Bioactivity

    3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM) . It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.

  • Target

    Glucokinase, Autophagy

  • Related Pathways

    Autophagy, Metabolism

  • CAS Number

    18446

  • Purity

    0.9967

  • Molecular Formula

    C13H10N2O

  • Molecular Weight

    210.23

  • SMILES

    O=C(\C=C\c1cccnc1)c1ccncc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound