(3R,5S) -Fluvastatin - CAS 155229-75-7

(3R,5S) -Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.

Others, Autophagy, HMG-CoA Reductase

Autophagy, Others, Metabolism

155147

C24H26FNO4

411.47

C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3

-20°C

Ice Packs

Small Compound