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4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine - CAS 2649012-21-3

4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine - CAS 2649012-21-3

MF-0015278-01

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Product Details

  • Bioactivity

    4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

  • Target

    CRFR, CFTR

  • Related Pathways

    GPCR/G Protein, Membrane transporter/Ion channel

  • CAS Number

    2648988

  • Purity

    0.9902

  • Molecular Formula

    C27H28ClFN2OS

  • Molecular Weight

    483.04

  • SMILES

    [C@@H](N(CC#C)C1=NC(=C(C)S1)C2=C(Cl)C=C(OC)C(C)=C2)(CC3CC3)C4=CC(F)=C(C)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound