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4-Amino-1- (2-C-methyl-β-D-ribofuranosyl) -1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile - CAS 847651-51-8

4-Amino-1- (2-C-methyl-β-D-ribofuranosyl) -1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile - CAS 847651-51-8

SKU:MF-0058255-01

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  • Bioactivity

    4-Amino-5-cyano-1- (2-β-C-methyl-β-D-ribofuranosyl) -7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy, particularly against indolent lymphoid malignancies. Its anticancer properties primarily stem from the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].

  • Target

    Others, Nucleoside Antimetabolite/Analog

  • Related Pathways

    Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

  • CAS Number

    847592

  • Molecular Formula

    C13H15N5O4

  • Molecular Weight

    305.29

  • SMILES

    C[C@]1(O)[C@H](N2C=3C(C(C#N)=CN3)=C(N)N=C2)O[C@H](CO)[C@H]1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound