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Molfinity

4-Br-Bnlm - CAS 1654775-71-9

4-Br-Bnlm - CAS 1654775-71-9

SKU:MF-0058393-01

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  • Bioactivity

    4-Br-Bnlm, with an EC 50 of 0.96 μM, acts as a selective inhibitor of glucose-regulated protein 94 (Grp94) . It effectively reduces both mutant and wild-type misfolded myocilin proteins in cells, thereby enhancing the clearance of toxic forms of myocilin and diminishing myocilin toxicity [1] [2].

  • Target

    Others, HSP

  • Related Pathways

    Others, Cytoskeletal Signaling, Metabolism

  • CAS Number

    1654775-71-9

  • Molecular Formula

    C20H18BrClN2O4

  • Molecular Weight

    465.72

  • SMILES

    C(OC)(=O)C1=C(CCC=2N(CC3=CC=C(Br)C=C3)C=CN2)C(Cl)=C(O)C=C1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound