4-CPPC - CAS 29553-70-6

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM) .1It is selective for MIF-2 over MIF-1 (IC50= 450 μM) . It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.

MIF, Others, CD74

Immunology/Inflammation, Others

29553-70-6

0.9803

C14H9NO6

287.22

OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O

-20°C

Ice Packs

Small Compound