4-Desmethyl-2-methyl celecoxib - CAS 170569-99-0

4-Desmethyl-2-methyl celecoxib (Compound 1g) is an orally active and selective cyclooxygenase-2 (COX-2) inhibitor, with an IC50 value of 0.069 μM. It possesses anti-inflammatory, analgesic, and antipyretic properties and can reduce prostaglandin synthesis. This compound is a promising candidate for research into inflammatory diseases and pain-related conditions, such as rheumatoid arthritis and osteoarthritis.

COX

Immunology/Inflammation, Neuroscience

170470

C17H14F3N3O2S

381.372

O=S(=O)(N)C1=CC=C(C=C1)N2N=C(C=C2C=3C=CC=CC3C)C(F)(F)F

-20°C

Ice Packs

Small Compound