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4'-Ethynyl-2'-deoxyadenosine - CAS 306305-07-7

4'-Ethynyl-2'-deoxyadenosine - CAS 306305-07-7

SKU:MF-0004201-01

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  • Bioactivity

    4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, demonstrates potent activity against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.

  • Target

    HIV Protease, Reverse Transcriptase, Others

  • Related Pathways

    Microbiology/Virology, Others, Proteases/Proteasome

  • CAS Number

    306305-07-7

  • Molecular Formula

    C12H13N5O3

  • Molecular Weight

    275.26

  • SMILES

    NC1=C2C(N(C=N2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC=N1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound