4-FPBUA - CAS 2089636-93-9

4-FPBUA, a semi-synthetic analog of lichen acid, enhances the functionality of cell-based blood-brain barriers (BBB) and increases the transport of β-amyloid (Aβ) in monolayer cells. Additionally, it acts as an inhibitor of mTOR, enhancing cellular autophagy (Autophagy) which can reverse BBB disruption in vivo, making it relevant for research in Alzheimer's disease.

Autophagy, mTOR

PI3K/Akt/mTOR signaling, Autophagy

2089636-93-9

C31H23FO7

526.51

C[C@]12C=3C(OC1=CC(O)=C(C(C)=O)C2=O)=C(C(/C=C/C4=CC=C(C=C4)C5=CC=C(F)C=C5)=O)C(O)=C(C)C3O

-20°C

Ice Packs

Small Compound