4-hydroperoxy 2-Nonenal - CAS 7439-43-2

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

Others, Reactive Oxygen Species

Metabolism, Immunology/Inflammation, Others, NF-κB

7394

C9H16O3

172.224

CCCCCC(OO)\C=C\C=O

-20°C

Ice Packs

Small Compound