4-Hydroxyresveratrol - CAS 331443-00-6

4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene) is a resveratrol analog that variably induces the expression of pro-apoptotic genes such as p53 and Bax. It triggers apoptosis in SV40 virus-transformed WI38 cells (WI38VA), but not in WI38 cells. Additionally, 4-Hydroxyresveratrol significantly increases the expression of p53, GADD45, and Bax genes in WI38VA cells, while suppressing the expression of the bcl-2 gene.

Bcl-2 Family, Apoptosis, MDM-2/p53

Apoptosis

331443-00-6

C14H12O4

244.243

C(=C/C1=CC=C(O)C=C1)\C2=CC(O)=C(O)C(O)=C2

-20°C

Ice Packs

Small Compound