4-methoxylonchocarpin - CAS 51589-67-4

4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in macrophages and suppressed TNBS-induced colitis in mice.

NF-κB, TLR, Interleukin, TNF

Immunology/Inflammation, Apoptosis, NF-κB

51589-67-4

0.9867

C21H20O4

336.38

OC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O

-20°C

Ice Packs

Natural Product