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4-TM.P - CAS 2089575-84-6
4-TM.P - CAS 2089575-84-6
SKU:MF-0058883-01
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Product Details
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Bioactivity
4-TM.P binds to the minor groove of DNA, inhibiting the proliferation of K562 cancer cells with an IC50 of 25 μM. It causes cell cycle arrest at the G0/G1 phase and induces apoptosis (apoptosis) in K562 cells. 4-TM.P is applicable in leukemia research.
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Target
Apoptosis
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Related Pathways
Apoptosis
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CAS Number
2089485
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Molecular Formula
C18H24N2O2
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Molecular Weight
300.395
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SMILES
C(=C/C(OC(=O)C=1C=NC=CN1)C)\C=2C(C)(C)CCCC2C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound