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(4R,5S) -nutlin carboxylic acid - CAS 2306390-08-7
(4R,5S) -nutlin carboxylic acid - CAS 2306390-08-7
SKU:MF-0002909-01
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Product Details
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Bioactivity
(4R,5S) -Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].
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Target
Others, Ligand for E3 Ligase
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Related Pathways
Others, PROTAC
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CAS Number
2306390-08-7
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Molecular Formula
C32H32Cl2N4O6
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Molecular Weight
639.53
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SMILES
C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(O)=O)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC