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5- (2-Chloroacetamide) thalidomide - CAS 1957235-51-6

5- (2-Chloroacetamide) thalidomide - CAS 1957235-51-6

MF-0059206-01

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Product Details

  • Bioactivity

    5- (2-Chloroacetamide) thalidomide is an analog of Thalidomide. Thalidomide functions by recruiting E3 ligase for ubiquitination, leading to the degradation of specific proteins. This compound features a chloroacetamide moiety, which acts as a thiol-specific reactive group.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    1957178

  • Molecular Formula

    C15H12ClN3O5

  • Molecular Weight

    349.726

  • SMILES

    O=C(NC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3)CCl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC