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5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone - CAS 927406-46-0

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone - CAS 927406-46-0

SKU:MF-0059120-01

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  • Bioactivity

    5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from indigo. DDR inhibits the PI3K/AKT and NF-кB pathways, reducing the invasion and migration of cancer cells and exhibiting anticancer properties.

  • Target

    PI3K, NF-κB, Akt

  • Related Pathways

    Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, NF-κB

  • CAS Number

    927406-46-0

  • Molecular Formula

    C23H24O11

  • Molecular Weight

    476.43

  • SMILES

    O(C)C1=C2C(=C(O)C(OC)=C1O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)C(=O)C=C(O2)C4=CC=C(O)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product