5,6-Benzoflavone - CAS 6051-87-2

5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses anti-inflammatory and antioxidant activities, inhibits LPS-induced inflammation through the AKT/Nrf-2/HO-1-NF-kappaB signaling axis, inhibits TNF-α-induced ICAM-1 and VCAM-1 expression, which can be used to study neurodegenerative diseases.

Apoptosis, Antioxidant, Aryl Hydrocarbon Receptor

Apoptosis, Immunology/Inflammation, Oxidation-Reduction

5962

0.9988

C19H12O2

272.3

O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1

-20°C

Ice Packs

Natural Product