5 (6) -Carboxy-2′,7′-dichlorofluorescein diacetate - CAS 127770-45-0

5 (6) -Carboxy-2',7'-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5 (6) -carboxy-2',7', -dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.

Others, Reactive Oxygen Species

Metabolism, Others, NF-κB, Immunology/Inflammation

127770-45-0

C25H14Cl2O9

529.3

CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4cc(ccc34)C(O)=O)c2cc1Cl.CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4ccc(cc34)C(O)=O)c2cc1Cl

-20°C

Ice Packs

Dye-Reagents