(±) 5 (6) -DiHET lactone - CAS 213126-92-2

5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5 (6) -EET degrades into 5 (6) -DiHET and 5 (6) -δ-lactone, which can be converted to 5 (6) -DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41% and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger [L-NAME].

Others

Others

213032

C20H32O3

320.473

CCCCC\C=C/C\C=C/C\C=C/CC(O)C1CCCC(=O)O1

-20°C

Ice Packs

Small Compound