5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone - CAS 1353676-65-9

5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone demonstrated a strong anti-proliferative effect on ER-positive breast cancer MCF-7 cells in vitro, with an IC50 value of 4.41 μM. It significantly down-regulated the expression of estrogen receptor-α (ER-α) and inhibited tumor growth in the BCAP-37 human breast cancer cell line xenograft model.

Estrogen Receptor/ERR

Endocrinology/Hormones

1353676-65-9

C26H28O7

452.5

O=C1C(OC)=C(OC=2C1=C(O)C=C(O)C2CC=C(C)C)C=3C=C(O)C(O)=C(C3)CC=C(C)C

-20°C

Ice Packs

Natural Product