5,7-Dihydroxychromone - CAS 31721-94-5

1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5,7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.

Nrf2, PARP, Caspase, Anti-infection, Virus Protease

Immunology/Inflammation, Proteases/Proteasome, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic, Microbiology/Virology

31721-94-5

0.9976

C9H6O4

178.14

Oc1cc(O)c2c(c1)occc2=O

-20°C

Ice Packs

Natural Product