5-Benzyloxytryptamine - CAS 20776-45-8

5-Benzyloxytryptamine (5-BT) is a selective partial agonist of the 5-hydroxytryptamine 1D/1B (5-HT1D/1B) receptors, with an IC50 value of 40 nM for the bovine caudate nucleus 5-HT1D. It exhibits much lower affinity for other receptors (5-HT2 IC50 > 470 nM) . 5-Benzyloxytryptamine inhibits adenylate cyclase, leading to reduced neurotransmitter release and downregulation of cAMP signaling. It holds potential for research into diseases associated with neurotransmitter imbalances.

5-HT Receptor

GPCR/G Protein, Neuroscience

20723

C17H18N2O

266.34

O(C=1C=CC=2NC=C(C2C1)CCN)CC=3C=CC=CC3

-20°C

Ice Packs

Small Compound