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5-Hydrazinyl thalidomide hydrochloride - CAS 2803460-96-8
5-Hydrazinyl thalidomide hydrochloride - CAS 2803460-96-8
SKU:MF-0059537-01
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Product Details
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Bioactivity
5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analog characterized by a hydrazine group. It serves as a PROTAC linker to recruit E3 ligase for the ubiquitination of target proteins. The hydrazine group allows further derivatization through reactions with various carbonyl groups.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
2803356
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Molecular Formula
C13H13ClN4O4
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Molecular Weight
324.72
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SMILES
Cl.O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)NN)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC