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5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione - CAS 2589697-74-3

5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione - CAS 2589697-74-3

MF-0059546-01

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Product Details

  • Bioactivity

    5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione is a Thalidomide analog featuring a hydroxyl group, which serves as a versatile site for further derivatization. Thalidomide acts as an E3 ligase activator and facilitates the ubiquitination of specific proteins.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    2589620

  • Molecular Formula

    C14H12N2O5

  • Molecular Weight

    288.255

  • SMILES

    O=C1C2=CC=C(O)C=C2C(=O)N1C3C(=O)N(C(=O)CC3)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC