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5α-Hydroxy-6-keto cholesterol - CAS 13027-33-3

5α-Hydroxy-6-keto cholesterol - CAS 13027-33-3

SKU:MF-0043668-01

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  • Bioactivity

    5α-Hydroxy-6-keto cholesterol is a β-epoxide metabolite and cholesterol derivative produced in human bronchial epithelial cells (16-HBE) exposed to ozone. It inhibits cholesterol synthesis (IC50=350 nM) and exhibits cytotoxicity.

  • Target

    Endogenous Metabolite

  • Related Pathways

    Metabolism

  • CAS Number

    12991

  • Molecular Formula

    C27H46O3

  • Molecular Weight

    418.66

  • SMILES

    C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC(=O)[C@@]1(O)C[C@@H](O)CC2)[H])[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound