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5-hydroxy-6-methoxy (S) -Duloxetine - CAS 741693-79-8
5-hydroxy-6-methoxy (S) -Duloxetine - CAS 741693-79-8
SKU:MF-0049696
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Product Details
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Bioactivity
5-hydroxy-6-methoxy (S) -Duloxetine is a metabolite of (S) -duloxetine . It is formed from (S) -duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S) -Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.
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Target
Others
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Related Pathways
Others
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CAS Number
741606
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Molecular Formula
C19H21NO3S
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Molecular Weight
343.44
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SMILES
CNCC[C@H](Oc1cccc2c(O)c(OC)ccc12)c1cccs1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound