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5-hydroxy Diclofenac - CAS 69002-84-2
5-hydroxy Diclofenac - CAS 69002-84-2
SKU:MF-0059808-01
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$307.11 USD
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$307.11 USD
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Product Details
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Bioactivity
5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. Diclofenac is a non-selective COX inhibitor. It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 μM, respectively. Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively.
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Target
Others, Apoptosis, Drug Metabolite
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Related Pathways
Metabolism, Apoptosis, Others
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CAS Number
68916
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Molecular Formula
C14H11Cl2NO3
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Molecular Weight
312.15
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SMILES
OC(=O)Cc1cc(O)ccc1Nc1c(Cl)cccc1Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound