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Molfinity

5-Iodo-indirubin-3'-monoxime - CAS 331467-03-9

5-Iodo-indirubin-3'-monoxime - CAS 331467-03-9

SKU:MF-0004236-01

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  • Bioactivity

    5-Iodo-indirubin-3'-monoxime is a potent inhibitor of GSK-3β, CDK5/P25, and CDK1/cyclin B, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20, and 25 nM) .

  • Target

    CDK, GSK-3

  • Related Pathways

    PI3K/Akt/mTOR signaling, Stem Cells, Cell Cycle/Checkpoint

  • CAS Number

    331467-03-9

  • Molecular Formula

    C16H10IN3O2

  • Molecular Weight

    403.17

  • SMILES

    O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(I)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound