5- (Methoxycarbonyl) methyluridine - CAS 29428-50-0

5- (Methoxycarbonyl) methyluridine, a uracil derivative, is an important modifying nucleotide in the anticodon loop of yeast tRNAs, allowing tRNAs to be correctly pre-structured and bind to codons on mRNAs, and the lack of the mcm5U modification (e.g., in elp3 mutant strains) leads to increased protein aggregation.

Nucleoside Antimetabolite/Analog

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

29378

0.9971

C12H16N2O8

316.26

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(CC(OC)=O)=C2

-20°C

Ice Packs

Small Compound