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5-Methyl cromolyn disodium - CAS 1221154-42-2

5-Methyl cromolyn disodium - CAS 1221154-42-2

SKU:MF-0059645-01

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  • Bioactivity

    5-Methyl cromolyn (C5OH) disodium is a cromolyn analog that acts as an S100P inhibitor. It prevents the interaction between S100P and its receptor RAGE, hinders NF-κB activity and cell proliferation, and enhances apoptosis induced by Gemcitabine. In murine models with PDAC, 5-Methyl cromolyn disodium reduces tumor growth and metastasis, thereby extending survival. This compound is suitable for pancreatic cancer research, including studies on pancreatic ductal adenocarcinoma (PDAC) .

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1221110

  • Molecular Formula

    C25H18Na2O11

  • Molecular Weight

    540.38

  • SMILES

    O=C(C(OC1=CC=CC(OCCC(CCOC(C=CC=C2OC(C([O-])=O)=C3)=C2C3=O)O)=C14)=CC4=O)[O-].[Na+].[Na+]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound