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5-Methyl cromolyn disodium - CAS 1221154-42-2
5-Methyl cromolyn disodium - CAS 1221154-42-2
SKU:MF-0059645-01
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Product Details
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Bioactivity
5-Methyl cromolyn (C5OH) disodium is a cromolyn analog that acts as an S100P inhibitor. It prevents the interaction between S100P and its receptor RAGE, hinders NF-κB activity and cell proliferation, and enhances apoptosis induced by Gemcitabine. In murine models with PDAC, 5-Methyl cromolyn disodium reduces tumor growth and metastasis, thereby extending survival. This compound is suitable for pancreatic cancer research, including studies on pancreatic ductal adenocarcinoma (PDAC) .
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Target
Others
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Related Pathways
Others
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CAS Number
1221110
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Molecular Formula
C25H18Na2O11
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Molecular Weight
540.38
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SMILES
O=C(C(OC1=CC=CC(OCCC(CCOC(C=CC=C2OC(C([O-])=O)=C3)=C2C3=O)O)=C14)=CC4=O)[O-].[Na+].[Na+]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound