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5-Monobutyl methotrexate - CAS 66147-31-7
5-Monobutyl methotrexate - CAS 66147-31-7
SKU:MF-0059712-01
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Product Details
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Bioactivity
5-Monobutyl methotrexate is an antineoplastic antimetabolite with immunosuppressant properties. It is a TETRAHYDROFOLATE DEHYDROGENASE inhibitor and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
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Target
Others
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Related Pathways
Others
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CAS Number
66109
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Molecular Formula
C24H30N8O5
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Molecular Weight
510.55
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SMILES
NC=1C2=C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(OCCCC)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound