5-Octyl-α-ketoglutarate - CAS 1616344-00-3

In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate, also known as α-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free α-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases. It is used in experiments to increase levels of intracellular α-ketoglutarate. 5-Octyl-α-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathways, particularly in the context of glycolysis, hypoxia, and cancer.

Others, Histone Methyltransferase, E1/E2/E3 Enzyme

Ubiquitination, Chromatin/Epigenetic, Others

1616344-00-3

C13H22O5

258.31

C(C(OCCCCCCCC)=O)CC(C(O)=O)=O

-20°C

Ice Packs

Small Compound