5 (S),12 (S) -DiHETE - CAS 79056-01-2

5 (S),12 (S) -DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5 (S),12 (S) -DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12 (S) -HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5 (S),12 (S) -DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.

Others

Others

79056-01-2

C20H32O4

336.472

CCCCC\C=C/C[C@H](O)\C=C\C=C/C=C/[C@@H](O)CCCC(O)=O

-20°C

Ice Packs

Small Compound