5 (S) -HETE lactone - CAS 127708-42-3

5 (S) -HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5 (S) -HETE. The ability of (±) 5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 μM) may be entirely due to the 5 (S) isomer, but the enantiomers have not been tested separately.

Others, Drug Metabolite

Others, Metabolism

127663

C20H30O2

302.45

C(=C/C=C\C/C=C\C/C=C\CCCCC)\[C@H]1OC(=O)CCC1

-20°C

Ice Packs

Small Compound