5Z-7-Oxozeaenol - CAS 253863-19-3

5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF) -β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.

Src, PDGFR, MAPK, MEK, VEGFR, FLT, Antibiotic

MAPK, Angiogenesis, Microbiology/Virology, Tyrosine Kinase/Adaptors

253841

0.99

C19H22O7

362.37

COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O

-20°C

Ice Packs

Natural Product