6-Chloro-7-deazaguanine - CAS 84955-31-7

6-Chloro-7-deazaguanine (compound 63) is an inactive IKK molecule, lacking the essential 5-cyano group, and targets IKKα and IKKβ with Ki values exceeding 30 μM. IKKβ and IKKα are central molecules in the classical and non-classical NF-κB pathways, respectively.

IκB/IKK

NF-κB

84917

C6H5ClN4

168.584

ClC1=NC(=NC=2NC=CC12)N

-20°C

Ice Packs

Small Compound