6-Formylpterin - CAS 712-30-1

6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase (Ki ~0.6 nM) with potent neuroprotective effects against transient IRI in gerbils.6-Formylpterin induces intracellular ROS generation in HL-60 cells as well as apoptosis (6-Formylpterin inhibits the expression of iNOS, produces hydrogen peroxide intracellularly and restores the impaired bactericidal activity of human neutrophils.

Xanthine Oxidase, Antibacterial, NOS, Reactive Oxygen Species, Apoptosis, ROS

Apoptosis, Immunology/Inflammation, Metabolism, Microbiology/Virology, NF-κB

681

0.98

C7H5N5O2

191.15

Nc1nc(O)c2nc(C=O)cnc2n1

-20°C

Ice Packs

Small Compound