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6FC-GABA-Taxol - CAS 3055969-34-8
6FC-GABA-Taxol - CAS 3055969-34-8
SKU:MF-0060414-01
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Product Details
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Bioactivity
6FC-GABA-Taxol is a cell-permeable fluorescent probe created by linking 6FC with the anticancer drug paclitaxel (Taxol) through γ-aminobutyric acid (GABA) . It binds to microtubules in live cells, allowing imaging via confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without efflux inhibitors.
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Target
Others
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Related Pathways
Others
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CAS Number
3055927
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Molecular Formula
C61H61FN2O19
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Molecular Weight
1145.14
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SMILES
O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](OC(CCCNC(=O)C4=CC=5C(OC4=O)=CC(O)=C(F)C5)=O)C[C@]1(OC2)[H])C(=O)[C@H](OC(C)=O)C=6C(C)(C)[C@](O)([C@H]3OC(=O)C7=CC=CC=C7)C[C@H](OC([C@@H]([C@@H](NC(=O)C8=CC=CC=C8)C9=CC=CC=C9)O)=O)C6C)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Dye-Reagents