6PPD-Q - CAS 2754428-18-5

6PPD-Q (6PPD-Quinone) is an environmental pollutant that can target CNR2, CNR1, AA2AR, LCAT and TRPA1. Among them, CNR2 has the highest binding affinity and may act as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q can damage the sperm quality and induce the impairment of male reproductive ability in mice. 6PPD-Q can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolytic metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.

Endogenous Metabolite

Metabolism

2754405

0.994

C18H22N2O2

298.38

O=C1C=C(NC(C)CC(C)C)C(=O)C=C1NC=2C=CC=CC2

-20°C

Ice Packs

Natural Product