7-Hydroxyneolamellarin A - CAS 959662-26-1

7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α) . It effectively reduces the accumulation of HIF-1α protein and suppresses vascular epidermal growth factor (VEGF) transcriptional activity, making it valuable in cancer research [1].

VEGFR, HIF/HIF Prolyl-Hydroxylase, Others

Metabolism, Others, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic

959635

C24H19NO5

401.41

C(C(O)C1=CC=C(O)C=C1)(=O)N2C=C(C(=C2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4

-20°C

Ice Packs

Natural Product