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8,12-iso-iPF2α-VI - CAS 1445349-99-4
8,12-iso-iPF2α-VI - CAS 1445349-99-4
SKU:MF-0060745-01
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Product Details
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Bioactivity
8,12-iso-iPF2α-VI, an isoprostane, arises from non-enzymatic, free radical-induced peroxidation of membrane lipids. It is the predominant isoprostane formed during lipid peroxidation and serves as a biomarker for oxidative stress. Detectable in hepatic tissue post CCl4-induced oxidative damage, 8,12-iso-iPF2α-VI levels are also elevated in the urine, blood, and cerebrospinal fluid of Alzheimer's disease patients.
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Target
Others, Prostaglandin Receptor
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Related Pathways
Others, GPCR/G Protein, Immunology/Inflammation
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CAS Number
1445349-99-4
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Molecular Formula
C20H34O5
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Molecular Weight
354.5
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SMILES
C(=C/C(CCCC(O)=O)O)\[C@@H]1[C@H](C/C=C\CCCCC)[C@H](O)C[C@@H]1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound