8-Br-7-CH-cADPR - CAS 189876-06-0

8-Br-7-CH-cADPR (7-Deaza-8-bromo-cADPR) is an effective antagonist of cADPR. It can partially inhibit the calcium elevation induced by sTIR dimerization. Moreover, 8-Br-7-CH-cADPR significantly reduces axonal degeneration triggered by paclitaxel.

Calcium Channel

Metabolism, Membrane transporter/Ion channel

189876-06-0

C16H21BrN4O13P2

619.21

BrC=1N2C3=C(C1)C(=N)N(C=N3)[C@@]4(O[C@@]([C@@H](O)[C@H]4O)(COP(=O)(O)OP(=O)(O)OC[C@]5(O[C@@]2([C@H](O)[C@@H]5O)[H])[H])[H])[H]

-20°C

Ice Packs

Small Compound