8-Br-PET-cGMP - CAS 144510-04-3

8-Br-PET-cGMP is an agonist of type I cyclic GMP-dependent protein kinase (cGKI), which promotes the dimerization and activation of the catalytic activity of cGKI by binding to its regulatory domain. This compound is utilized to investigate the role of the cGMP signaling pathway in cell growth, vasodilation, and smooth muscle cell functions.

144510-04-3

C18H15BrN5O7P

524.22

BrC=1N(C2=C(N1)C(=O)N3C(N2)=NC(=C3)C4=CC=CC=C4)[C@H]5[C@H](O)[C@]6([C@](O5)(COP(=O)(O)O6)[H])[H]

-20°C

Ice Packs

Small Compound