8-CPT-Cyclic AMP (sodium salt) - CAS 93882-12-3

8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) and a potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an inhibitory concentration (IC50) of 0.9 μM. It also inhibits PDE III and PDE IV while significantly activating Epac, demonstrating diverse pharmacological activities [1] [2].

PDE, PKA, Others

Others, Tyrosine Kinase/Adaptors, Metabolism

93867

C16H14ClN5NaO6PS

493.79

NC1=C2C(N([C@@H]3O[C@@]4([H])[C@](OP([O-])(OC4)=O)([H])[C@H]3O)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1.[Na+]

-20°C

Ice Packs

Small Compound